Botulinum toxin (Botox) has been used for treatment of conditions caused by muscle over activity such as muscle spasms. Botox works by preventing muscle spasm.
Injecting Botox into muscle around the anus will cause it to relax and reduce muscle tension. This is reduce pain and increase blood flow to the fissure, allowing it to heal naturally.
Success rate for anal fissure healing is 7 out of every 10 treatments. Sometimes, the injections need to be repeated, which is successful in 5 out of every 10 treatments.
Botox injection is safe. Side effects is a small risk of temporary loss of control of flatulence (wind) which resolves after approximately 2 -3 months.